THE SEQUENCE AND A THREE-DIMENSIONAL STRUCTURAL ANALYSIS REVEAL SUBSTRATE SPECIFICITY AMONG SNAKE VENOM PHOSPHODIESTERASES

The Sequence and a Three-Dimensional Structural Analysis Reveal Substrate Specificity among Snake Venom Phosphodiesterases

(1) Background.Snake venom phosphodiesterases (SVPDEs) are among the least studied venom enzymes.In envenomation, they display various pathological Vibration Sensor effects, including induction of hypotension, inhibition of platelet aggregation, edema, and paralysis.Until now, there have been no 3D structural studies of these enzymes, thereby preve

read more